![]() ![]() These results suggest that Swiss 3T3 cells possess novel metabolic products of mevalonic acid metabolism that are formed by post-translational incorporation of isoprenoids into specific cell proteins. Other lines of evidence suggested that mevalonate was first converted to an isoprenoid compound, then covalently incorporated into proteins by way of a cycloheximide-insensitive mechanism. Search Schematic Finder Schematics Requested Manufacturer Countries Audio New Pictures. Control experiments indicated that authentic radioactive (R)-mevalonic acid was the active precursor. USA, build 1949, 13 pictures, 20 schematics, 9 tubes, United States of America, semiconductors, Broadcast. Further analysis by electrophoresis revealed that radioactivity was associated with a few specific proteins that had apparent molecular weights of 13,000-58,000. Dont forget to leave your rating and comment about this number, to help us improve our community database. Please check general information, community rating and reports about this phone number. ![]() ![]() Upon analyzing the radioactive material formed, we found that 40-50% of it was not extractable into lipid solvents, and that most of the lipid-insoluble material behaved like protein when treated with sodium dodecyl sulfate:chloroform:phenol, RNase, or proteinase K. 2707 S Diamond Bar Blvd Suite 102 Diamond Bar, CA 91765 (909) 839-2611 View Profile. 02-9730-9996 is a Landline phone number located in the city of Sydney in New South Wales. To search for other products of mevalonic acid that might account for these requirements we cultured Swiss 3T3 cells in the presence of mevinolin, an inhibitor of mevalonic acid biosynthesis, then labeled the cells with exogenous radioactive mevalonic acid. Our in-depth knowledge, multidisciplinary services, extensive resources, and quality standards assure your comfort and well-being. Previous studies have identified several cellular requirements for mevalonic acid that appear unrelated to cholesterol, dolichol, or ubiquinone. ![]()
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